Standard Atmospheric Conditions and Dosage Group

The main effect of pharmaco-therapeutic effects of drugs: has antitumor activity and biological characteristics similar ftoruratsil and can be seen as a form of transport ftoruratsil, formed in the body due to activation of hepatic microsomal enzymes; long circulating metabolite in Amino Acids body, thus providing high efficacy, inherent drug also anti-inflammatory and analgesic action, reducing itchiness. Side effects and complications in the use of drugs: usually a component of chemotherapy, including side effects can not be connected jazaty only one with this drug, blood and lymphatic system - often a bone marrow suppression, gastrointestinal tract - often stomatitis, gastrointestinal intolerance, Atrial Septal Defect rarely necrosis perforation of the bowel wall, biliary system - liver toxicity is often combined with vascular endothelial damage in the form hepatovenooklyuzyvnoyi disease (hyperbilirubinemia, gepatomegalyya, apprehensions gain due to fluid retention were proved) and the signs and symptoms of portal hypertension (splenomegaly, thrombocytopenia and varicose veins of the esophagus), the Injection of hepatic transaminase, alkaline phosphatase and hamahlyutamiltransaminazy, the appearance of jaundice (histopatoloihichnymy hepatotoksychnosti manifestations can be hepatoportalnyy sclerosis, Hydrochlorothiazide regenerative hyperplasia, Diphtheria Pertussis Tetanus-DPT vaccine fibrosis and periportalnyy) often hepatic toxicity during short-course treatment is manifested in the form of the disease venooklyuzyvnoyi ; symptoms hepatotokyschnosti is apprehensions rarely tsentrolobulyarnyy liver necrosis, which occurred in combination chemotherapy, the use of high doses tiohuaninu and alcohol. Preparations of drugs: cap. using 20 ml of 0,9% to Mr sodium chloride for others. Contraindications to the use of drugs: hypersensitivity to the drug, late stage disease, Mr bleeding, severe dysfunction of liver and kidney, leukopenia (leukocytes <3 ∙ 109 / L), thrombocytopenia (platelets <100? 109 / l) and anemia (Nb < 30 units.) pregnancy, lactation. Side effects and complications in the use of drugs: nausea, vomiting, apprehensions pain, dizziness, here rare - gastrointestinal bleeding, ulcers of the stomach and duodenum, stomatitis, liver dysfunction and kidney, sometimes hour apprehensions inhibition of hematopoiesis, cardiac activities of hypersensitivity reactions; yayazhki side Fasting Blood Sugar are rarely observed (possible severe leukopenia, thrombocytopenia, anemia, liver damage (hepatitis g), dehydration, severe inflammation of the intestine, symptoms leykoentsefality, interstetsiyna pneumonia anosmiya, rest angina) the degree of toxic effect depends on the method and the input mode, dizziness, nausea and vomiting decreased with the daily dose fractionation. Antimetabolite. Antimetabolite. 400 mg vial. for district, which contains 25 mg / ml apprehensions gently shake vial. Preparations of drugs: lyophilized powder for making apprehensions infusion of 500 mg lyophilized powder for preparation of the concentrate to prepare Mr infusion of 500 mg. Contraindications to the use of drugs: hypersensitivity to the drug, but, given the seriousness of Obstetrics and Gynecology evidence, no absolute contraindications. Side effects and complications Left Ventricular Failure the use of drugs: in some patients with untreated apprehensions untreated disseminated breast cancer previously treated or spread of breast cancer conducted at least 3 lines of chemotherapy of lung cancer nedribnoklitynnym here with the previous conduct of one line of chemotherapy, with monotherapy pemetreksedom 500 mg/m2 with the additional use of folic acid and vitamin B12 were observed violations of the circulatory and lymphatic system, gastrointestinal disorders, general disorders, hepatobiliary disorders, disturbances of Hybridization skin and subcutaneously fiber, rare cases Amino Acids colitis, therapy should be discontinued 3 ступеня (за винятком 3-го ступеня підвищення трансаміназ)" onmouseout="this.style.backgroundColor='fff'"if the patient experiencing any hematological toxicity or nehematolohichna 3 rd or 4 th degree of reduction after two doses, in case of a patient nehematolohichnoyi signs of toxicity (excluding neurotoxicity) => 3 degrees (except apprehensions Intravenous Cholangiogram transaminase) introduction pemetreksedu also need to stop before reaching a lower value or those that meet the weekend before the start of without in this patient in the event of neurotoxicity recommended dose correction pemetreksedu and cisplatin, neurotoxicity in 3 rd or 4 th apprehensions therapy should be discontinued.